The browser you are using is not supported by this website. All versions of Internet Explorer are no longer supported, either by us or Microsoft (read more here: https://www.microsoft.com/en-us/microsoft-365/windows/end-of-ie-support).

Please use a modern browser to fully experience our website, such as the newest versions of Edge, Chrome, Firefox or Safari etc.

New imaging method sheds light on Alzheimer’s disease

Photo of Oxana Klementieva.

Oxana Klementieva and her colleagues in Lund and at Synchrotron SOLEIL in France have used a new method, optical photothermal spectroscopy (O-PTIR) to study protein structures in neurons from mice affected by early stage Alzheimer’s disease. 

“We saw that the structure of the protein changes in different ways depending on where in the nerve cell it is. So far, there have been no methods that can produce these types of images, giving us insight into what the first molecular changes in neurons actually look like in Alzheimer's disease”, says Oxana Klementieva.

Their work has been published in the journal Advanced Science, and featured on the cover page.