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Portrait of Jonas Tegenfeldt. Photo: Kennet Ruona

Jonas Tegenfeldt

Professor, Coordinator Nanobiology & Neuronanoscience

Portrait of Jonas Tegenfeldt. Photo: Kennet Ruona

Polarization anisotropy of DNA in nanochannels


  • Fredrik Persson
  • Fredrik Westerlund
  • Jonas O. Tegenfeldt
  • Anders Kristensen

Summary, in English

The local alignment of DNA stretched in nanofluidic channels is measured using polarization sensitive detection. With increased degree of stretching the polarization anisotropy increases both in the deGennes and the Odijk regime. The technique is expected to find use in studies of, for example, local conformational changes in polymer physics in confined spaces, studies of protein-DNA interactions and compactation of DNA.


  • Solid State Physics

Publishing year






Document type

Conference paper


  • Nanofluidics
  • Optics
  • Polarization anisotropy
  • Polymer physics

Conference name

12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008

Conference date

2008-10-12 - 2008-10-16

Conference place

San Diego, CA, United States