Your browser has javascript turned off or blocked. This will lead to some parts of our website to not work properly or at all. Turn on javascript for best performance.

The browser you are using is not supported by this website. All versions of Internet Explorer are no longer supported, either by us or Microsoft (read more here: https://www.microsoft.com/en-us/microsoft-365/windows/end-of-ie-support).

Please use a modern browser to fully experience our website, such as the newest versions of Edge, Chrome, Firefox or Safari etc.

Portrait of Jonas Tegenfeldt. Photo: Kennet Ruona

Jonas Tegenfeldt

Professor, Coordinator Nanobiology & Neuronanoscience

Portrait of Jonas Tegenfeldt. Photo: Kennet Ruona

Polarization anisotropy of DNA in nanochannels

Author

  • Fredrik Persson
  • Fredrik Westerlund
  • Jonas O. Tegenfeldt
  • Anders Kristensen

Summary, in English

The local alignment of DNA stretched in nanofluidic channels is measured using polarization sensitive detection. With increased degree of stretching the polarization anisotropy increases both in the deGennes and the Odijk regime. The technique is expected to find use in studies of, for example, local conformational changes in polymer physics in confined spaces, studies of protein-DNA interactions and compactation of DNA.

Department/s

  • Solid State Physics

Publishing year

2008-01-01

Language

English

Pages

668-670

Document type

Conference paper

Keywords

  • Nanofluidics
  • Optics
  • Polarization anisotropy
  • Polymer physics

Conference name

12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008

Conference date

2008-10-12 - 2008-10-16

Conference place

San Diego, CA, United States

Status

Published