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Portrait of Jonas Tegenfeldt. Photo: Kennet Ruona

Jonas Tegenfeldt

Professor, Coordinator Nanobiology & Neuronanoscience

Portrait of Jonas Tegenfeldt. Photo: Kennet Ruona

Orientational correlations in confined DNA

Author

  • E. Werner
  • F. Persson
  • F. Westerlund
  • Jonas Tegenfeldt
  • B. Mehlig

Summary, in English

We study how the orientational correlations of DNA confined to nanochannels depend on the channel diameter D by means of Monte Carlo simulations and a mean-field theory. This theory describes DNA conformations in the experimentally relevant regime where the Flory-de Gennes theory does not apply. We show how local correlations determine the dependence of the end-to-end distance of the DNA molecule upon D. Tapered nanochannels provide the necessary resolution in D to study experimentally how the extension of confined DNA molecules depends upon D. Our experimental and theoretical results are in qualitative agreement.

Department/s

  • Solid State Physics

Publishing year

2012

Language

English

Pages

041802-041802

Publication/Series

Physical Review E (Statistical, Nonlinear, and Soft Matter Physics)

Volume

86

Issue

4

Document type

Journal article

Publisher

American Physical Society

Topic

  • Condensed Matter Physics

Status

Published

ISBN/ISSN/Other

  • ISSN: 1539-3755