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Portrait of Jonas Tegenfeldt. Photo: Kennet Ruona

Jonas Tegenfeldt

Professor, Coordinator Nanobiology & Neuronanoscience

Portrait of Jonas Tegenfeldt. Photo: Kennet Ruona

Tunable separation and DNA manipulation in metal coated pillar arrays

Author

  • Jason P. Beech
  • Kevin Keim
  • Bao Dang Ho
  • Oskar Ström
  • Carlotta Guiducci
  • Jonas O. Tegenfeldt

Summary, in English

Implementing electrically connected metal-coated posts in a Deterministic Lateral Displacement (DLD) device and applying electric fields, we use electrokinetics to achieve tunable particle separations and to trap and manipulate DNA. The strength of DLD stems from its typically binary behavior. Particles move in one out of two trajectories based on their effective size. For particles that are close to the threshold size, a minute external force is sufficient to nudge the particles from one trajectory to another. Dielectrophoresis (DEP) provides such a force and also gives specificity based on the dielectric properties of the particles.

Department/s

  • NanoLund

Publishing year

2018

Language

English

Pages

2090-2093

Publication/Series

22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018

Volume

4

Document type

Conference paper

Publisher

Chemical and Biological Microsystems Society

Topic

  • Other Materials Engineering

Keywords

  • Deterministic lateral displacement
  • Dielectrophoresis
  • Integrated electrodes
  • Particle separation

Conference name

22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018

Conference date

2018-11-11 - 2018-11-15

Conference place

Kaohsiung, Taiwan, Province of China

Status

Published

ISBN/ISSN/Other

  • ISBN: 9781510897571