Melting mapping in nanochannels
Summary, in English
We demonstrate direct visualization of melting mapping of DNA stretched in nanoscale channels using standard staining methods and epifluorescence microscopy to gain information on the local AT/GC ratio along large DNA molecules. Our development opens up a novel route to mapping of large-scale genomic variations.
- Solid State Physics
12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008
2008-10-12 - 2008-10-16
San Diego, CA, United States