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Portrait of Jonas Tegenfeldt. Photo: Kennet Ruona

Jonas Tegenfeldt

Professor, Coordinator Nanobiology & Neuronanoscience

Portrait of Jonas Tegenfeldt. Photo: Kennet Ruona

Label-free cytometry - Novel sorting parameters and opportunities

Author

  • Jonas O. Tegenfeldt
  • Jason P. Beech
  • Stefan Holm

Summary, in English

The inherent properties of cells and micro-organisms is an under-explored source of specificity for particle sorting. In contrast to standard immunolabeling it allows us to perform fractionation without any chemical preparation of the sample. This improves the accessibility and affordability of the technology. Our contribution in the field is to extend the scope of deterministic lateral displacement (DLD) from merely a very powerful size-based sorting scheme so that it is used to sort with respect to several other physical parameters. We have explored parameters such as shape, deformability, dielectric properties, secretion and density with potential applications in bacteriology, parasitology and oncology.

Department/s

  • NanoLund
  • Solid State Physics

Publishing year

2014-01-01

Language

English

Pages

242-245

Publication/Series

18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014

Document type

Conference paper

Publisher

Chemical and Biological Microsystems Society

Topic

  • Other Physics Topics
  • Analytical Chemistry

Keywords

  • Biophysics
  • Label free
  • Microfluidics
  • Particle sorting

Conference name

18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014

Conference date

2014-10-26 - 2014-10-30

Conference place

San Antonio, United States

Status

Published

ISBN/ISSN/Other

  • ISBN: 9780979806476