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Portrait of Jonas Tegenfeldt. Photo: Kennet Ruona

Jonas Tegenfeldt

Professor, Coordinator Nanobiology & Neuronanoscience

Portrait of Jonas Tegenfeldt. Photo: Kennet Ruona

Viable/non-viable cell assay using electrokinetic deterministic lateral displacement

Author

  • Bao D. Ho
  • Jason P. Beech
  • Jonas O. Tegenfeldt

Summary, in English

To evaluate the effect of antibiotic drugs, it is important that the cells that are killed can be sorted from the cells that are resistant to the antibiotics. Here we report a simple label-free method for the continuous separation of viable/non-viable cells using Electrokinetic Deterministic Lateral Displacement. In general, this opens up for continuous sorting of a population of cells that is homogeneous in size but heterogeneous in surface charge or dielectric properties, properties that change as a function of viability.

Department/s

  • Solid State Physics
  • NanoLund

Publishing year

2019

Language

English

Pages

596-597

Publication/Series

23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019

Document type

Conference paper

Publisher

Chemical and Biological Microsystems Society

Topic

  • Cell and Molecular Biology
  • Biophysics

Keywords

  • Deterministic Lateral Displacement
  • DLD
  • Electrokinetics
  • Label-free cell separation

Conference name

23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019

Conference date

2019-10-27 - 2019-10-31

Conference place

Basel, Switzerland

Status

Published

ISBN/ISSN/Other

  • ISBN: 9781733419000